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Symbol
Name
ID

Il5
interleukin 5
MGI:96557

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Asthma
Disease(s) Associated with IL5	Asthma
asthma

Mouse Phenotypes

abnormal eosinophil differentiation

peritoneal inflammation

increased spleen weight

decreased eosinophil cell number

increased eosinophil cell number

increased neutrophil cell number

abnormal mast cell morphology

increased mature B cell number

abnormal T cell number

increased lymphocyte cell number

increased monocyte cell number

increased leukocyte cell number

abnormal B-1 B cell morphology

abnormal spleen morphology

abnormal mast cell physiology

decreased IgE level

decreased circulating interleukin-5 level

enlarged lymph nodes

increased interferon-gamma secretion

decreased interleukin-5 secretion

granulomatous inflammation

abnormal susceptibility to infection

increased susceptibility to parasitic infection

Availability

Mouse Genotype

Il5^tm1Anjm/Il5^tm1Anjm

Il5^tm1Kopf/Il5^tm1Kopf

Il5^tm1Ktk/Il5^tm1Ktk

Il5^tm3Anjm/Il5^tm3Anjm

Il5^{tm1.1(icre)Lky}/Il5⁺

Il5^tm1Ktk/Il5⁺

Tg(Cd3d-Il5)NJ.1638Nal/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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